| 斯洛伐克 | Sī luò fá kè | Slovak; Slovak republic (from 1992); Slovakia |
| 斯洛伐克语 | Sī luò fá kè yǔ | Slovak (language) |
| 斯洛文尼亚 | Sī luò wén ní yà | Slovenia |
| 斯洛文尼亚共和国 | Sī luò wén ní yà gòng hé guó | Republic of Slovenia |
| 斯洛维尼亚 | Sī luò wéi ní yà | Slovenia |
| 斯特凡诺普洛斯 | Sī tè fán nuò pǔ luò sī | Stephanopoulos (e.g. former Clinton aide George Stephanopoulos) |
| 斯特拉斯堡 | Sī tè lā sī bǎo | Strasbourg |
| 斯特拉特福 | Sī tè lā tè fú | Stratford (place name); Stratford-upon-Avon, UK city in Warwickshire and birthplace of William Shakespeare 莎士比亚 |
| 斯瓦希里 | Sī wǎ xī lǐ | Swahili |
| 斯瓦希里语 | Sī wǎ xī lǐ yǔ | Swahili (language); Kiswahili |
| 斯瓦特 | Sī wǎ tè | Swat province in Pakistani Northwest Frontier |
| 斯瓦特谷地 | Sī wǎ tè gǔ dì | Swat valley in Pakistani Northwest Frontier |
| 斯当东 | Sī dāng dōng | Stanton (name); Baron George Stanton, the second-in-command of the Macartney Mission of 1793 |
| 斯皮尔伯格 | Sī pí ěr bó gé | Steven Spielberg (1946-), US film director |
| 斯福尔瓦尔 | Sī fú ěr wǎ ěr | Svolvær (city in Nordland, Norway) |
| 斯科普里 | Sī kē pǔ lǐ | Skopje |
| 斯维尔德洛夫 | Sī wéi ěr dé luò fū | Yakov Mikhailovich Sverdlov (1885-1919), Bolshevik organizer, ordered the murder of the Tsar's family in 1918, died of Spanish influenza |
| 斯考特 | Sī kǎo tè | Scott (name) |
| 斯芬克司 | Sī fēn kè sī | Sphinx (Egyptian mythical beast) |
| 斯芬克斯 | sī fēn kè sī | sphinx (myth.) |
| 斯莱特林 | Sī lái tè lín | Slytherin (Harry Potter) |
| 斯蒂文 | Sī dì wén | Steven (name); Simon Stevin (1548-1620), Flemish engineer and mathematician, played a key role in introducing the decimal system to Europe |
| 斯蒂文森 | Sī dì wén sēn | Stevenson or Stephenson (name) |
| 斯蒂芬 | Sī dì fēn | Stephen or Steven (name) |
| 斯蒂芬・哈珀 | Sī dì fēn · Hā pò | Stephen Harper (1959-), Canadian politician, prime minister from 2006 |
| 斯诺 | Sī nuò | Snow (name); Edgar Snow (1905-1972), American journalist, reported from China 1928-1941, author of Red Star Over China |
| 斯诺克 | sī nuò kè | snooker |
| 斯通亨治石栏 | Sī tōng hēng zhì shí lán | Stonehenge stone circle |
| 斯里巴加湾港 | Sī lǐ Bā jiā wān gǎng | Bandar Seri Begawan, capital of Brunei |
| 斯雷布雷尼察 | Sī léi bù léi ní chá | Srebrenica, Bosnia-Herzegovina |